I have successfully done what you want to do with a Gigabyte Z170-HD3 motherboard, installed ESXi 6.5 U1 to a NVme SSD 240G with VMs: XPE/DSM 6.1(passthrough integrated SATA controller), WIN10 as HTPC also play PC games(passthrough a NVIDIA GTX1060 and integrated USB controller),LEDE as my major router(it is more powerful, instead NETGEAR R7000 just as a ap to provide wifi),and other Linuxs.Since you want a Itx board,so I suggest ASTROCK Z270-itx.In order to passthrough the NVIDIA graphic card successfull, you need add a VM parameter: "hypervisor.cpu.v0 = FALSE" (if not do this, you can see the graph card in WIN10 device manager but can't use it, this step confused me for a long time, I found the solution in Google's search results). 通过我的 SM919 上的 Tapatalk发言